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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RANGAP1
All Species:
36.67
Human Site:
Y550
Identified Species:
62.05
UniProt:
P46060
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46060
NP_002874.1
587
63542
Y550
N
H
M
V
Q
Q
D
Y
F
P
K
A
L
A
P
Chimpanzee
Pan troglodytes
XP_001169198
587
63551
Y550
N
H
M
V
Q
Q
D
Y
F
P
K
A
L
A
P
Rhesus Macaque
Macaca mulatta
XP_001099367
1074
115836
Y604
N
H
M
V
Q
Q
D
Y
F
P
K
A
L
A
P
Dog
Lupus familis
XP_538355
1323
142434
Y550
N
H
M
V
Q
Q
D
Y
F
P
K
A
L
A
P
Cat
Felis silvestris
Mouse
Mus musculus
P46061
589
63598
Y552
N
H
V
V
R
Q
D
Y
F
P
K
A
L
A
P
Rat
Rattus norvegicus
NP_001012199
431
46388
E395
E
E
E
E
E
E
E
E
E
P
Q
Q
R
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509116
589
63641
Y552
N
H
A
A
Q
Q
D
Y
F
P
K
S
L
A
P
Chicken
Gallus gallus
NP_001006237
580
63057
Y543
N
H
M
V
Q
Q
D
Y
F
P
K
S
L
A
P
Frog
Xenopus laevis
O13066
580
62889
Y543
N
H
M
V
Q
Q
N
Y
F
P
K
S
L
A
S
Zebra Danio
Brachydanio rerio
NP_001070084
570
61996
Y529
E
H
A
V
K
Q
S
Y
F
P
R
E
H
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VIW3
596
66051
Y560
K
E
V
F
H
S
D
Y
D
V
K
N
C
R
F
Honey Bee
Apis mellifera
XP_395378
580
63771
Y535
E
I
V
S
Q
K
D
Y
F
L
Q
E
T
R
N
Nematode Worm
Caenorhab. elegans
P34342
960
105635
D847
R
I
D
R
L
D
I
D
F
E
S
R
F
Q
E
Sea Urchin
Strong. purpuratus
XP_001185909
387
41323
P351
G
G
Q
E
S
K
D
P
H
L
Q
V
K
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
52.7
41.4
N.A.
88.6
66.6
N.A.
83.6
81.7
67.9
60.8
N.A.
32.3
43.6
25
40.7
Protein Similarity:
100
99.1
53.7
43
N.A.
95.5
70.6
N.A.
91.5
91.6
83.8
78
N.A.
53.1
59.9
38.2
54.8
P-Site Identity:
100
100
100
100
N.A.
86.6
6.6
N.A.
80
93.3
80
40
N.A.
20
26.6
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
86.6
100
93.3
53.3
N.A.
26.6
46.6
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
8
0
0
0
0
0
0
0
36
0
58
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
8
0
0
8
72
8
8
0
0
0
0
0
0
% D
% Glu:
22
15
8
15
8
8
8
8
8
8
0
15
0
0
8
% E
% Phe:
0
0
0
8
0
0
0
0
79
0
0
0
8
0
8
% F
% Gly:
8
8
0
0
0
0
0
0
0
0
0
0
0
15
0
% G
% His:
0
65
0
0
8
0
0
0
8
0
0
0
8
0
0
% H
% Ile:
0
15
0
0
0
0
8
0
0
0
0
0
0
8
0
% I
% Lys:
8
0
0
0
8
15
0
0
0
0
65
0
8
0
0
% K
% Leu:
0
0
0
0
8
0
0
0
0
15
0
0
58
0
0
% L
% Met:
0
0
43
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
58
0
0
0
0
0
8
0
0
0
0
8
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
8
0
72
0
0
0
0
50
% P
% Gln:
0
0
8
0
58
65
0
0
0
0
22
8
0
8
0
% Q
% Arg:
8
0
0
8
8
0
0
0
0
0
8
8
8
15
0
% R
% Ser:
0
0
0
8
8
8
8
0
0
0
8
22
0
0
15
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
15
% T
% Val:
0
0
22
58
0
0
0
0
0
8
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
79
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _